Talk:Human papillomavirus infection

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"Genital cancer"

The "Genital cancer" row in HPV types table is confusing. Does it refer to female genitals, male genitals, or both? The impact of HPV types is quite different.

I suspect the current content applies to female genitals but doesn't seem to fit very well with penile cancer. For instance, in this study ^[1] analyzing the role of HPV in penile cancer, HPV-16 was the most frequent HPV type detected in both HPV-positive cancers (68.7%) and HGSILs (79.6%), followed by HPV-6 (3.7%) but in the table HPV-6 isn't even present. Another study ^[2] found single-viral infection of the following types in patients with penile cancer: 45, 35, 18, 52, 68, 31, 53, 6. All of which (except type 6) are currently present in the table. However I haven't been able to find any reference linking penile cancer with the remaining types (33, 39, 51, 56, 58, 59, 26, 66, 73, 82), perhaps these types are only associated with female genitals? Maybe a good solution would be to split "Genital cancer" in two rows, one for female genitals and one for male genitals. Robert1dB (talk) 22:57, 29 November 2022 (UTC)[reply]

References

"Oropharyngeal cancer"

Apologies if I'm missing something obvious (I'm not an expert in the field or even health/biology for that matter), but based on information I found on the net it would seem there's more to HPV and "Oropharyngeal cancer" than just type 16. Quoting from this meta-study ^[1]: "The most common HPV type detected in oral cancers is HPV16. A notable outlier is a study from South Africa which detected only HPV18, and not HPV16, in patients with oral cancer. HPV18 was detected in a smaller percentage of oral cancers, some oral carcinomas had dual infections with HPV16/18. Rarer types detected in oral cancers were HPV8, HPV31, HPV38, and HPV66." Robert1dB (talk) 23:07, 29 November 2022 (UTC)[reply]

References

^ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394168/

Redundant statement

"While cases of warts have been described since the time of ancient Greece, their viral cause was not known until 1907." occurs twice in the article. Mansell (talk) 06:35, 19 March 2023 (UTC)[reply]

"Cervical Cancer"

"HPV is necessary for cervical cancer to occur." Looking through the citation linked for this information, there is no information which supports this claim. There are other articles which say HPV negative cervical cancer can occur. ^[1] Stew240 (talk) 09:38, 18 April 2023 (UTC)[reply]

References

^ https://pubmed.ncbi.nlm.nih.gov/34073478/

Discovered

Why no mention of when HPV was discovered ? 70.190.65.59 (talk) 04:41, 26 April 2023 (UTC)[reply]

[1] ttps://www.sciencedirect.com/science/article/abs/pii/S0302283815012154?via%3Dihub

[2] ttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850485/

[3] ttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394168/

[4] ttps://pubmed.ncbi.nlm.nih.gov/34073478/

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